40+ longevity interventions,
ranked by the evidence.
A physician's verdict on every supplement, peptide, and protocol you've been told you need. 140+ citations. Zero affiliate links.
$50 · Lifetime access · Quarterly updates included
Already purchased? Log in →Most of what you've been told about living longer is selling something.
- NAD+ infusions$100
- Supplement stack$70
- Peptide injections$300
- Biological-age test$400
- Gym membership$50
- Creatine$9
- Vitamin D$5
- Fish oil$12
The things that do make money — exotic supplements, unproven peptides, $400 testing panels — have the weakest evidence in the whole literature. Often, no human evidence at all.
This playbook exists to tell you which is which.
Exercise — the single biggest mortality predictor in the literature.
The complete chapter from the Playbook. 11 citations. Sent now to your inbox.
Every intervention gets a verdict.
Six examples below. The full playbook covers 40+ interventions, and every claim has a numbered citation to a peer-reviewed study you can look up.
All 40+ interventions get this treatment. $50, lifetime access.
Get the Playbook →Things you'll learn.
- 01Which commercially available peptides have zero human safety trials — and which three are the exceptions.
- 02The $20 blood test that predicts cardiovascular risk better than any $400 longevity panel.
- 03What the human trials on intermittent fasting actually show (it’s not what Instagram tells you).
- 04The free intervention that beats every supplement on the market for all-cause mortality.
- 05Why cold plunges feel good — and why the longevity data doesn’t support them.
- 06The longevity paradox of growth hormone: what makes you look young may shorten your life.
- 07My personal protocol — what I take, what I refuse to take, and why.
Thirteen sections. Every claim cited.
- 01The Things That Actually Work
- 02Supplements & Compounds
- 03Fasting & Dietary Protocols
- 04Peptides — The Wild West
- 05Cold & Heat Exposure
- 06Sleep
- 07Hormones
- 08Advanced Testing
- 09GLP-1 / GIP Agonists
- 10The Supplement Deep-Dive
- 11Mindset & Social Connection
- 12My Personal Protocol
- 13Quarterly Updates
An honest disclaimer.
You won't find
- Affiliate links to supplement companies. Not now, not later.
- Dosing protocols for compounds with no human safety data.
- “Top 10 longevity hacks” listicles optimized for the Gram.
- Confidence whenever the intervention calls for nuance (which is very common).
You will find
- Every claim backed by a peer-reviewed citation you can verify.
- An honest “we don't know” wherever the data is genuinely unclear.
- Clear verdicts: proven, promising, unproven, or skip.
- Quarterly updates as the science evolves — included for life.
The author.
Ramy Khalil, MD is double board-certified in internal medicine and clinical informatics. He reads medical data for a living. He wrote this because he kept correcting the same supplement misinformation in clinic, one patient at a time, and decided to write it down once.
- —Founder, Clinicly — comprehensive direct primary care for Dubai expats.
- —Founder, Continuum Overnight Primary Care — live virtual care for Americans at night.
- —Dr. Khalil has no supplement line or clinic that sells these interventions. There is no affiliate revenue or industry sponsorship. None.
“My patients were spending hundreds of dollars a month on stuff that was either unproven or unsafe. I give them this resource to help guide our discussions on what's worth their time and money. I'm now offering it to anyone who wants to read it.”
Read the Playbook.
No upsells. Lifetime access.
One-time. Lifetime web access.
Less than one month of the supplements you might reconsider after reading the evidence.
Every quarter I revisit the evidence. Things get upgraded. Things get downgraded. New interventions get added. You get all of it, forever, for the $50 you pay today.
- —Lifetime web access to the full playbook
- —All 13 sections with 140+ peer-reviewed citations
- —Personal protocol breakdown
Secure checkout via Stripe. If after reading the Playbook you don't change your mind about at least one thing you're currently spending money on, email me for a refund. Thirty days.
Before you read.
Is this medical advice?+
No. This is one physician's evidence-based assessment. It's designed to help you make informed decisions with your own doctor.
What makes this different from free longevity content?+
Every claim has a numbered citation. There are no affiliate links, no sponsored products, and no financial incentive to recommend anything. My only conflict of interest is that I want you to read this.
How are quarterly updates delivered?+
Updated directly in the web version — included with your purchase for life. Each update covers what’s been upgraded, downgraded, and newly on radar.
Can I get a refund?+
If the playbook doesn’t change how you think about at least one intervention, I’ll refund you within 30 days of purchase.
Do you sell supplements or run a longevity clinic?+
No. I run a direct primary care practice. Zero financial incentive to recommend any specific product.
Why are you charging for this? Shouldn’t it be free?+
I don’t have a supplement line. Nobody sponsored this or told me what to include or leave out. That’s the point — and that’s also why it costs something.
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